Dr. Spuches Invited Lectures

“Investigating the thermodynamics that drive binding of Ca(II) and Cd(II) to human cardiac troponin C: A tale of two metals.” Presented at Marshall University Department of Chemistry Virtual Colloquium. March 1st, 2022.

“Investigating the thermodynamics that drive binding of Ca(II) and Cd(II) to human cardiac troponin C”. Presented at the Emerging Research by Investigators at Primarily Undergraduate Institutions Symposium, Fall National Meeting of the American Chemical Society, 2021.

“The Heat is On: Investigating the thermodynamics that drive binding of Ca(II) and Cd(II) to cardiac troponin C”. Presented at the Bioinorganic Chemistry in the South Symposium, SERMACS 2017. Charlotte, NC, November 2017.

Wake-Tech LHC STEM Speaker Series: “The Role of Metals in Biology.” Presented at Wake Technical Community College, Durham, NC. February 25th, 2016.

“Lessons learned from the enthalpy, entropy, and heat capacity of metal ions binding to Biomolecules: A detailed study of copper (II) binding to Aβ peptides.”  Presented at the Inorganic Chemistry of Neurobiology, Immunology and Bioenergy: New Faces Symposium, 248th ACS National Meeting.  San Francisco, CA. August 2014.

“The Heat is On: Studying the Thermodynamics of Metals Binding to Proteins and Peptides.” Presented at the Eastern North Carolina Section of the American Chemical Society. Greenville, NC. April 2014.

“Essential Metal Ion Interactions with Peptides and Proteins: The Good, The Bad, and the Ugly.” Presented at the following institutions:

  • Winthrop University Department of Chemistry, Biochemistry, Physics, and Geology. February 9th, 2012.
  • Davidson College Department of Chemistry. February 10th, 2012.
  • University of North Carolina at Charlotte Chemistry Department. February 13th, 2012.

“My Journey from Student to Professor: How the Karen Wetterhahn Award Inspired My Career Choices”. Presented at the 25th Anniversary of the NIEHS Superfund Basic Program, Raleigh, NC. October 2012.

School of Pharmacology and Toxicology Lecture Series, ECU Brody School of Medicine.  March 30th, 2011. “Thermodynamic Investigation of Copper Binding to the Amyloid-Beta (Aβ) Peptides.” 

Receptor Mechanisms Discussion Group.  National Institute of Environmental Health Sciences (NIEHS).  April 19, 2009. “Thermodynamics of Zinc, Cobalt and Arsenic Binding to the DNA Binding Domain of Glucocorticoid Receptor: The Good, the Bad and the Ugly.”

Hitchner Lecture Series.  University of Maine, Orono.  September 29th, 2008. “Mechanisms of Arsenic Toxicity:  Thermodynamic and Spectroscopic Investigations of Arsenite and Monomethylarsenite Binding to the DNA Binding Domain of Glucocorticoid Receptor.”

Frontiers in Environmental Sciences Lecture Series.  National Institute of Environmental Health Sciences (NIEHS).  September 19th, 2008. “Mechanisms of Arsenic Toxicity:  Thermodynamic and Spectroscopic Investigations of Arsenite and Monomethylarsenite Binding to the DNA Binding Domain of Glucocorticoid Receptor.”

Distinguished Lecturer Seminar.  National Institute of Environmental Health Sciences (NIEHS).  October 24th, 2005. “Thermodynamics of Zinc, Cobalt and Arsenic Binding to the DNA Binding Domain of Glucocorticoid Receptor:  The Good, the Bad and the Ugly.”

Seventh Annual Karen Wetterhahn Address. Superfund Basic Research Program’s Annual Meeting. Seattle, Washington. November 4th, 2004. “Thermodynamic Properties of AsIII-Thiol Interactions: Biological Implications for Arsenic Toxicity.”